ICJIM

The Intercontinental Journal of Internal Medicine aims to publish issues related to all fields of internal medicine of the highest scientific and clinical value at an international level and accepts articles on these topics. This journal is indexed by indices that are considered international scientific journal indices (DRJI, ESJI, OAJI, etc.). According to the current Associate Professorship criteria, it is within the scope of International Article 1-d. Each article published in this journal corresponds to 5 points.

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Case Report
A rare food poisoning: clostridium botulinum
Botulismus is a gram-positive anaerobic, spore-forming bacterium commonly found in soil. Exotaxins secreted by Clostridium bolulinum bacteria are heat-labile and irreversibly block the release of acetylcholine at the cholinergic ends of presynaptic and autonomic nerves at the neuromuscular junction after ingestion with food. The incubation period of botulismus is between 18-38 hours, and the first finding is blurred vision and diplopia symptoms due to the involvement of the eye muscles. The most important point in its treatment is early diagnosis and rapid administration of antitoxin. In this article, a case who was successfully treated in our intensive care unit with the diagnosis of botulismus poisoning is presented.


1. Sobel J. Diagnosis and treatment of botulism: a century later, clinicalsuspicion remains the cornerstone. Clin Infect Dis. 2009; 48: 1674-1675. Barash JR, Arnon SS. A novel strain of Clostridium botulinumthat produces type B and type H botulinum toxins. J Infect Dis2014;209(2):183-91.
2. Rasetti-Escargueil C, Lemichez, E, Popoff MR. Public health riskassociated with botulism as foodborne zoonoses.Toxins.2019;12(1):17.
3. Gao QY, Huang YF, Wu JG, et al. A review of botulism in China.Biomed Environ Sci. 1990;3(3):326-336
4. Meurens F, Carlin F, Federighi M, Filippitzi ME, Fournier M, FravaloP, Woudstra, C. Clostridium botulinum type C, D, C/D, and D/C: Anupdate.Frontiers in Microbiology,2023;13:1099184.
5. Harvey SM, Sturgeon J, Dassey DE. Botulism due to Clostridium baratiitype F toxin. . J Clin Microbiol. 2002;40(6):2260-2266.
6. Horowitz BZ. Botulinum Toxin. Critical Care Clin. 2005;21(4): 825-39.
7. Yoshida K. Botulinum toxin therapy for oromandibular dystonia andother movement disorders in the stomatognathic system.Toxins. 2022;14(4):282.
8. Dutton JJ, Buckley EG. Botulinum toxin in the management ofblepharospasm. Arch Neurol. 1986;43(4):380-382.
9. Benevenia R, Arnaboldi S, Dalzini E, Todeschi S, Bornati L, Saetti F,Losio MN. Foodborne botulism survey in Northern Italy from 2013 to2020: Emerging risk or stable situation? Food Control. 132, 2022;108520.
10. Aysal F, Deymeer F, Serdaroğlu P, Öge AE, Çakır N, Tütüncü A,Özdemir C. Botulizm: Dört Olgu Nedeniyle Klinik ve Elektrofizyolojisi.Klin Gelisim. 1995;8:3761-3765.
11. Cherington M. Botulism Ten Years Experience. Arch Neurol.1974;30(6):432-437.
12. Ropper AH, Brown RH. Adams and Victor’s Principles of Neurology.Çeviri Editörü: Murat Emre. 8. Baskı, Ankara: Öncü Basımevi, 2005;p. 1016-1045.
13. Sanders DB. Electrophysiologic study of disorders of neuromusculartransmission. In: Aminoff MJ (Ed) Electrodiagnosis in ClinicalNeurology. 3. Edition, New York: Churchill Livingstone Inc. 1992: p.347-348.
14. Jubelt B. Merritt’s Neurology. Çeviri editörü: Barış Baslo, CandanGürses. 11. Baskı, Ankara: Öncü Basımevi, 2008; p. 259-261
15. Borkowsky W, Wilfert MC. Botulism in infants. In: Infectious Diseasesof Children. Krugman Katz SL, Gershon AA, Wilfert CM (Eds)Philadelphia:Mosby Year Book, 1991; p. 22.
16. Lonati, D, Flore, L, Vecchio, et al. Clinical management of foodbornebotulism poisoning in emergency setting: An Italian case series. Clin.Toxicol. 2015;53:338.
17. Harjpal P, Menon S, Kovela RK. Impact of neuro physiotherapeuticreformation in a teenager agonizing with Guillain-Barre syndromelinked with COVID-19 infection.Cureus.2022;14(8).
Volume 1, Issue 3, 2023
Page : 73-75
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