ICJIM

The Intercontinental Journal of Internal Medicine aims to publish issues related to all fields of internal medicine of the highest scientific and clinical value at an international level and accepts articles on these topics. This journal is indexed by indices that are considered international scientific journal indices (DRJI, ESJI, OAJI, etc.). According to the current Associate Professorship criteria, it is within the scope of International Article 1-d. Each article published in this journal corresponds to 5 points.

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Review
Diagnosis and treatment of hepatic encephalopathy - review
Hepatic encephalopathy is observed in patients with liver dysfunction. Therefore, chronic liver disease patients are more affected. Due to reduced liver function, neurotoxins generated by damaged intestinal flora reach the brain. Hepatic encephalopathy can be classified according to the degree of symptoms. Ammonia concentration is thought to be important in pathogenesis. Its early phases can be diagnosed with a variety of tests. and it is possible to resolve and eliminate hepatic encephalopathy with imaging and treatment.


1. Ginès P, Krag A, Abraldes JG, Solà E, Fabrellas N, Kamath PS. Liver cirrhosis.Lancet. 2021;398(10308):1359-1376. doi:10.1016/S0140-6736(21)01374-X
2. Walter KL. What is cirrhosis? JAMA. 2023;330(4):386. doi:10.1001/jama.2023.8935
3. Zhou WC, Zhang QB, Qiao L. Pathogenesis of liver cirrhosis. World JGastroenterol. 2014;20(23):7312-7324. doi:10.3748/wjg.v20.i23.7312
4. Butterworth RF. Hepatic encephalopathy in cirrhosis: pathology andpathophysiology. Drugs. 2019;79(Suppl 1):17-21. https://doi.org/10.1007/s40265-018-1017-0
5. Frenette CT, Levy C, Saab S. Hepatic encephalopathy-relatedhospitalizations in cirrhosis: transition of care and closing the revolvingdoor. Dig Dis Sci. 2022;67(6):1994-2004. doi:10.1007/s10620-021-07075-2
6. Bajaj JS, Gentili A, Wade JB, Godschalk M. Specific challenges ingeriatric cirrhosis and hepatic encephalopathy. Clin GastroenterolHepatol. 2022;20(8):S20-S29. https://doi.org/10.1016/j.cgh.2022.04.035.
7. Mandiga P, Foris LA, Bollu PC. Hepatic encephalopathy. In: StatPearls.Treasure Island (FL): StatPearls Publishing: 2023.
8. R. Bacon B. Chapter 44. Cirrhosis and its complications. In: Kasper D,Fauci A, Hauser S, Longo D, Jameson JL, Loscalzo J, eds. Harrison’sGastroenterology and Hepatology. 3rd ed. McGraw-Hill Education:2017:469.
9. Lu K. Cellular pathogenesis of hepatic encephalopathy: an update.Biomolecules. 2023;13(2):396. doi:10.3390/biom13020396
10. Nardelli S, Gioia S, Faccioli J, Riggio O, Ridola L. Hepatic encephalopathy- recent advances in treatment and diagnosis. Expert Rev GastroenterolHepatol. 2023;17(3):225-235. doi: 10.1080/17474124.2023.2183386.
11. Vilstrup H, Amodio P, Bajaj J, et al. Hepatic encephalopathy in chronicliver disease: 2014 practice guideline by the American Association forthe study of liver diseases and the European Association for the study ofthe liver. Hepatology. 2014;60(2):715-735. doi: 10.1002/hep.27210.
12. Hızarcıoğlu Gülşen H, Özen H. Hepatik ensefalopati. In: AltunbaşakŞ, editör. Çocuklarda Ensefalopati. 1. Baskı. Türkiye Klinikleri: 2021:p.86-94.
13. Thabut D, Bouzbib C, Meunier L, et al. Diagnosis and managementof hepatic encephalopathy: the French recommendations. Liver Int.2023;43(4):750-762. doi: 10.1111/liv.15510.
14. Thanapirom K, Wongwandee M, Suksawatamnuay S, et al.Psychometric hepatic encephalopathy score for the diagnosis ofminimal hepatic encephalopathy in Thai cirrhotic patients. J Clin Med.2023;12(2):519. doi: 10.3390/jcm12020519
15. Weissenborn K, Ennen JC, Schomerus H, Rückert N, Hecker H.Neuropsychological characterization of hepatic encephalopathy. JHepatol. 2001;34(5):768-773. doi: 10.1016/s0168-8278(01)00026-5.
16. Amodio P, Campagna F, Olianas S, et al. Detection of minimalhepatic encephalopathy: normalization and optimization of thepsychometric hepatic encephalopathy score. A neuropsychologicaland quantified EEG study. J Hepatol. 2008;49(3):346-353. doi: 10.1016/j.jhep.2008.04.022.
17. Goldbecker A, Weissenborn K, Hamidi Shahrezaei G, et al.Comparison of the most favoured methods for the diagnosis ofhepatic encephalopathy in liver transplantation candidates. Gut.2013;62(10):1497-1504. doi: 10.1136/gutjnl-2012-303262.
18. Kircheis G, Hilger N, Häussinger D. Value of critical flicker frequencyand psychometric hepatic encephalopathy score in diagnosis of low-grade hepatic encephalopathy. Gastroenterol. 2014;146(4):961-969.doi: 10.1053/j.gastro.2013.12.026.
19. Kircheis G, Nilius R, Held C, et al. Therapeutic efficacy of L-ornithine-L-aspartate infusions in patients with cirrhosis and hepaticencephalopathy: results of a placebo-controlled, double-blind study.Hepatol. 1997;25(6):1351-1360. doi: 10.1002/hep.510250609.
20. Romero-Gómez M, Córdoba J, Jover R, et al. Value of the critical flickerfrequency in patients with minimal hepatic encephalopathy. Hepatol.2007;45(4):879-885. doi: 10.1002/hep.21586.
21. Karakaş S, Erdoğan E, Sak L, et al. Stroop test TBAG form:standardisation for Turkish culture, reliability and validity. J Clin Psy.1999;2(2):75-88.
22. Agarwal A, Taneja S, Chopra M, Duseja A, Dhiman RK. Animalnaming test - a simple and accurate test for diagnosis of minimalhepatic encephalopathy and prediction of overt hepatic encephalopathy.Clin Exp Hepatol. 2020;6(2):116-124. doi: 10.5114/ceh.2019.95105.
23. Erbay MF. Hepatik ensefalopati. Trd Sem. 2023;11(1):1-6. doi: 10.4274/trs.2023.223686.
24. Bellafante D, Gioia S, Faccioli J, Riggio O, Ridola L, Nardelli S. Old and newprecipitants in hepatic encephalopathy: a new look at a field in continuousevolution. J Clin Med. 2023;12(3):1187. doi: 10.3390/jcm12031187.
25. Ohnishi K, Sato S, Saito M, et al. Clinical and portal hemodynamicfeatures in cirrhotic patients having a large spontaneous splenorenaland/or gastrorenal shunt. Am J Gastroenterol. 1986;81(6):450-455.
26. Nardelli S, Riggio O, Gioia S, Puzzono M, Pelle G, Ridola L.Spontaneous porto-systemic shunts in liver cirrhosis: clinical andtherapeutical aspects. World J Gastroenterol. 2020;26(15):1726-1732.doi: 10.3748/wjg. v26.i15.1726
27. Amesur NB, Novelli P. Transjugular intrahepatic portosystemic shunt.In: StatPearls. Treasure Island (FL): StatPearls Publishing: 2023.
28. Dazıroğlu MEÇ, Yıldıran H. Intestinal dysbiosis and probiotic use:its place in hepatic encephalopathy in cirrhosis. Ann Gastroenterol.2023;36(2):141-148. doi: 10.20524/aog.2023.0776.
29. Kanbakan A. Acilci gözüyle hepatik ensefalopati. Updated January 3, 2019.Available from: https://acilci.net/acilci-gozuyle-hepatik-ensefalopati/.
30. Yu X, Jin Y, Zhou W, et al. Rifaximin modulates the gut microbiotato prevent hepatic encephalopathy in liver cirrhosis withoutimpacting the resistome. Front Cell Infect Microbiol. 2022;11:1427.doi: 10.3389/fcimb.2021.761192
Volume 1, Issue 4, 2023
Page : 106-108
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