ICJIM
Intercontinental Journal of Internal Medicine

The Intercontinental Journal of Internal Medicine aims to publish issues related to all fields of internal medicine of the highest scientific and clinical value at an international level and accepts articles on these topics. This journal is indexed by indices that are considered international scientific journal indices (DRJI, ESJI, OAJI, etc.). According to the current Associate Professorship criteria, it is within the scope of International Article 1-d. Each article published in this journal corresponds to 5 points.

eISSN: 2980-0846
Creative Commons CC BY-NC-ND 4.0 International License.
EndNote Style

Online Manuscript System

Index
Case Report
A case of myeloid sarcoma with duodenal involvement presenting with exrtahepatic cholestasis
Abstract
Myeloid sarcoma (MS) is a hematologic malignancy composed of myeloblasts or immature myeloid cells presenting in the extramedullary region. MS frequently involves bone, soft tissue, skin, lymph nodes, as well as the genitourinary and gastrointestinal systems. We wanted to present a case of MS presenting with duodenal involvement. A 22-year-old male patient presented with abdominal pain and jaundice. Laboratory values of total bilurubin: 7.75 mg/dl, indirect bilurubin: 6.7 mg/dl, GGT: 215 U/L. ERCP showed dilated choledochal dilatation with migrated stent and stenosis at the distal end. The existing stent was removed and a 10 FR 12 cm biliary plastic stent was placed proximal to the stenosis. Since hyperemic, erosion lesions were observed in the mouth of Oddi and duodenum, biopsies were taken from that region. The biopsy result was reported as primary duodenal myeloid sarcoma. MS should be considered in gastrointestinal lesions.

Keywords : Myeloid sarcoma, duodenum, cholestasis

Download Article


1. Pramanik R, Tyagi A, Chopra A, Kumar A, Vishnubhatla S, Bakhshi S. Myeloid sarcoma predicts superior outcome in pediatric AML; can cytogenetics solve the puzzle? Clin Lymphoma Myeloma Leuk. 2018; 18(6):e249-e254.
2. Yilmaz AF, Saydam G, Sahin F, Baran Y. Granulocytic sarcoma: a systematic review. Am J Blood Res. 2013;3(4):265-270.
3. Han Y, Jung HK, Chang JY, et al. Identification of distinctive clinical significance in hospitalized patients with endoscopic duodenal mucosal lesions. Korean J Intern Med. 2017;32(5):827-835.
4. Gupta S, Chawla I, Singh V, Singh K. Granulocytic sarcoma (chloroma) presenting as colo-colic intussusception in a 16-year-old boy: an unusual presentation. BMJ Case Rep. 2014;2014:bcr2014206138.
5. Vagholkar K, Mathew T. Adenocarcinoma of the small bowel: a surgical dilemma. Saudi J Gastroenterol. 2009;15(4):264-267. doi: 10.4103/1319-3767.56105
6. Costamagna G, Familiari P, Marchese M, Tringali A. Endoscopic biliopancreatic investigations and therapy. Best Pract Res Clin Gastroenterol. 2008;22(5):865-881.
7. Al-Khateeb H, Badheeb A, Haddad H, Marei L, Abbasi S. Myeloid sarcoma: clinicopathologic, cytogenetic, and outcome analysis of 21 adult patients. Leuk Res Treatment. 2011;2011:523168. doi: 10.4061/2011/523168
8. Modi G, Madabhavi I, Panchal H, et al. Primary vaginal myeloid sarcoma: a rare case report and review of the literature.Case Rep Obstet Gynecol.2015:957490. doi: 10.1155/2015/957490
9. Menasce LP, Banerjee SS, Beckett E, Harris M. Extra-medullary myeloid tumour (granulocytic sarcoma) is often misdiagnosed: a study of 26 cases.Histopathology.1999;34(5):391-398.
10. Kwan LY, Targan SR, Shih DQ. A case of steroid-dependent myeloid granulocytic sarcoma masquerading as Crohn’s disease. World J Gastroenterol. 2011;17(19):2446-2449.
11. Yamauchi K, Yasuda M. Comparison in treatments of nonleukemic granulocytic sarcoma: report of two cases and a review of 72 cases in the literature. Cancer. 2002;94(6):1739-1746.
12. Sun R, Samie AA, Theilmann L. A patient with a tumor of the ileocecal valve. Gastroenterol. 2011;141(6):2278. doi: 10.1053/j.gastro.2010.11.046
Article available in :
Volume 2, Issue 2, 2024
Page : 39-41
https://doi.org/10.51271/ICJIM-0033
Article Information
Received : 10 May 2024
Accepted : 22 May 2024
Published : 29 May 2024
Corresponding Author :

Mehmet Ali Erdoğan: Department of Gastroenterology, Faculty of Medicine, İnönü University, Malatya, Turkiye

[email protected]
Citation : Erdoğan MA. A case of myeloid sarcoma with duodenal involvement presenting with exrtahepatic cholestasis. Intercont J Int Med. 2024;2(2):39-41.

Read: 672
Cited: 0
Download : 115
_Footer