ICJIM
Intercontinental Journal of Internal Medicine

The Intercontinental Journal of Internal Medicine aims to publish issues related to all fields of internal medicine of the highest scientific and clinical value at an international level and accepts articles on these topics.

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Original Article
Carbapenem resistance profile of Escherichia coli and Klebsiella pneumoniae in our hospital
Abstract
Aims: This study aimed to evaluate the resistance rates of Escherichia coli (E. coli) and Klebsiella pneumoniae (K. pneumoniae) strains isolated from hospitalized patients in our hospital between 2011 and 2014 against carbapenem antibiotics.
Methods: A total of 5266 E. coli and 1360 K. pneumoniae strains isolated from different clinical samples were included in the study. Identification and antibiotic susceptibility tests were performed using the BD Phoenix 100 (Becton Dickinson, USA) automated system. Carbapenem resistance rates were evaluated according to imipenem, meropenem and ertapenem resistance.
Results: Carbapenem resistance was detected at a higher rate in K. pneumoniae strains compared to E. coli both bacteria were most frequently isolated from internal medicine ward and urine samples. Ertapenem stood out as the most resistant antibiotic. An increasing trend in carbapenem resistance was noted throughout the study.
Conclusion: The increasing carbapenem resistance observed in K. pneumoniae strains necessitates the development of more careful and effective strategies regarding antibiotic use in the management of nosocomial infections.

Keywords : Antibiotic resistance, Enterobacteriaceae, Carbapenem

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Article available in :
Volume 3, Issue 2, 2025
Page : 26-29
https://doi.org/10.51271/ICJIM-0053
Article Information
Received : 05 Nis 2025
Accepted : 27 Nis 2025
Published : 26 May 2025
Corresponding Author :

Resul Ekrem Akbulut: Department of Medical Microbiology, Faculty of Medicine, Sivas Cumhuriyet University, Sivas, Turkiye

[email protected]
Citation : Akbulut RE, Bakıcı MZ. Carbapenem resistance profile of Escherichia coli and Klebsiella pneumoniae in our hospital. Intercont J Int Med. 2025;3(2):26-29.

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